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  2. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    A schematic for long bone endochondral ossification. In developing bones, ossification commences within the primary ossification center located in the center of the diaphysis (bone shaft), [5] where the following changes occur: The perichondrium surrounding the cartilage model transforms into the periosteum. During this transformation, special ...

  3. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).

  4. Ossification center - Wikipedia

    en.wikipedia.org/wiki/Ossification_center

    An ossification center is a point where ossification of the hyaline cartilage begins. The first step in ossification is that the chondrocytes at this point become hypertrophic and arrange themselves in rows. [1] The matrix in which they are imbedded increases in quantity, so that the cells become further separated from each other.

  5. Development of joints - Wikipedia

    en.wikipedia.org/wiki/Development_of_joints

    Cells at the center of this interzone region undergo cell death to form the joint cavity, while surrounding mesenchyme cells will form the articular capsule and supporting ligaments. The process of endochondral ossification, which converts the cartilage models into bone, begins by the twelfth week of embryonic development.

  6. Osteochondroprogenitor cell - Wikipedia

    en.wikipedia.org/wiki/Osteochondroprogenitor_cell

    Conditional inactivation of TGF-βr2 of osteochondroprogenitor cells in the cranial neural crest resulted in faster osteoprogenitor differentiation and disorganised chondrogenesis. [6] TGF-β determines and regulates cell lineages during endochondral ossification through Sox9 and Runx2 signalling pathways.

  7. Chondrogenesis - Wikipedia

    en.wikipedia.org/wiki/Chondrogenesis

    A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele

  8. Today’s NYT ‘Strands’ Hints, Spangram and Answers for Sunday ...

    www.aol.com/today-nyt-strands-hints-spangram...

    If there is already an active hint on the board, a hint will show that word’s letter order. Related: 300 Trivia Questions and Answers to Jumpstart Your Fun Game Night.

  9. Bone remodeling - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling

    Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).