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Bioactive glasses have been synthesized through methods such as conventional melting, quenching, the sol–gel process, flame synthesis, and microwave irradiation.The synthesis of bioglass has been reviewed by various groups, with sol-gel synthesis being one of the most frequently used methods for producing bioglass composites, particularly for tissue engineering applications.
Therefore, the apatite formation on the surface of biomaterials, soaked in the SBF solution, is considered a successful development of novel bioactive materials. [5] The SBF technique for surface modification of metallic implants is usually a time-consuming process, and obtaining uniform apatite layers on substrates takes at least 7 days, with ...
Bioactive metallic glass is a subset of bioactive glass, wherein the bulk material is composed of a metal-glass substrate and is coated with bioactive glass in order to make the material bioactive. The reasoning behind the introduction of the metallic base is to create a less brittle, stronger material that will be permanently implanted within ...
In biology, a substrate is the surface on which an organism (such as a plant, fungus, or animal) lives.A substrate can include biotic or abiotic materials and animals. For example, encrusting algae that lives on a rock (its substrate) can be itself a substrate for an animal that lives on top of the algae.
One well known example of a bioassay is the "canary in the coal mine" experiment. [10] To provide advance warning of dangerous levels of methane in the air, miners would take methane-sensitive canaries into coal mines. If the canary died due to a build-up of methane, the miners would leave the area as quickly as possible.
A bioactive compound is a compound that has an effect on a living organism, tissue or cell, usually demonstrated by basic research in vitro or in vivo in the laboratory. While dietary nutrients are essential to life, bioactive compounds have not been proved to be essential – as the body can function without them – or because their actions are obscured by nutrients fulfilling the function.
The concentration of the substrate or product is recorded in time after the initial fast transient and for a sufficiently long period to allow the reaction to approach equilibrium. Progress curve experiments were widely used in the early period of enzyme kinetics, but are less common now. Transient kinetics experiments. In these experiments ...
The formation of neocartilage can also be induced with bioactive glass by using an in vitro culture of chondrocyte-seeded hydrogels and can serve as a subchondral substrate for tissue-engineered osteochondral constructs. [1] The borate-based bioactive glass has controllable degradation rates in order to match the rate at which actual bone is ...