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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
The serotonin antagonist cyproheptadine is the recommended initial therapy, although there have been no controlled trials demonstrating its efficacy for SS. [ 9 ] [ 69 ] [ 70 ] Despite the absence of controlled trials, there are a number of case reports detailing apparent improvement after people have been administered cyproheptadine. [ 9 ]
AH-1058 is a lipophilic antiarrhythmic calcium channel blocker synthesized by the Pharmaceutical Research Laboratories of Ajinomoto Co., Inc in Kawasaki, Japan. [1] It is derived from cyproheptadine, a compound with known antiserotonic, antihistaminic and calcium channel blocking properties.
3356 15558 Ensembl ENSG00000102468 ENSMUSG00000034997 UniProt P28223 P35363 RefSeq (mRNA) NM_001165947 NM_000621 NM_001378924 NM_172812 RefSeq (protein) NP_000612 NP_001159419 NP_001365853 NP_766400 Location (UCSC) Chr 13: 46.83 – 46.9 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse The 5-HT 2A receptor is a subtype of the 5-HT 2 receptor that belongs to the serotonin receptor ...
CHART #4: SIDE-BY-SIDE COMPARISON OF REPUBLICAN CANDIDATESÕ HEALTH PLANS By Susan J. Blumenthal, M.D., Jessica B. Rubin, Michelle E. Treseler, Jefferson Lin, and David Mattos*
Triflupromazine (Vesprin) is an antipsychotic medication of the phenothiazine class. Among different effects of triflupromazine indication for use of this drug is severe emesis and severe hiccups.
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PSYLO-4001 is a non-hallucinogenic serotonin 5-HT 2A receptor agonist and psychoplastogen which is under development for the treatment of depressive disorders such as major depressive disorder.