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When of gradual onset, symptoms may include loss of bladder control, mild lower abdominal pain, and a weak urine stream. [1] Those with long-term problems are at risk of urinary tract infections. [1] Causes include blockage of the urethra, nerve problems, certain medications, and weak bladder muscles. [1]
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
Treatment options include conservative treatment, behavioral therapy, bladder retraining, [36] pelvic floor therapy, collecting devices (for men), fixer-occluder devices for incontinence (in men), medications, and surgery. [37] Both nonpharmacological and pharmacological treatments may be effective for treating UI in non-pregnant women. [16]
Anticholinergic medications, which target the neurotransmitters that control urination Beta-3 agonists, which relax the smooth muscle in your bladder and reduce the urge to urinate
The bladder wall muscle overactivity results in sporadic bladder muscle contraction, which increases pressure in the bladder and decreases the volume of urine the bladder can hold. [2] If NDO is not treated, increased pressure in the bladder can put the upper urinary tract at risk of harm, including possible permanent damage to the kidneys. [2]
Trospium chloride is a muscarinic antagonist used to treat overactive bladder. [3] It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed.
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