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Setting aside other factors (e.g., balancing selection, and genetic drift), the equilibrium number of deleterious alleles is then determined by a balance between the deleterious mutation rate and the rate at which selection purges those mutations. Mutation–selection balance was originally proposed to explain how genetic variation is ...
The adaptive value can be measured by contribution of an individual to the gene pool of their offspring. The adaptive values are approximately calculated from the rates of change in frequency and mutation–selection balance. [2]
The Haldane-Muller theorem of mutation–selection balance says that the load depends only on the deleterious mutation rate and not on the selection coefficient. [6] Specifically, relative to an ideal genotype of fitness 1, the mean population fitness is exp ( − U ) {\displaystyle \exp(-U)} where U is the total deleterious mutation rate ...
Balancing selection refers to a number of selective processes by which multiple alleles (different versions of a gene) are actively maintained in the gene pool of a population at frequencies larger than expected from genetic drift alone. Balancing selection is rare compared to purifying selection. [1]
Wilhelm T. Preyer, a pioneer of child psychology, was heavily inspired by Darwin's work and approached the mental development of children from an evolutionary perspective. [14] However, evolutionary theory has had a limited impact on developmental psychology as a whole, [5] and some authors argue that even its early influence was minimal. [15]
The ice skating legend made headlines last year when he had an estate sale to get rid of most of his possessions, but there was one item he simply had to keep.
At the same time, new mutations occur, resulting in a mutation–selection balance. The exact outcome of the two processes depends both on the rate at which new mutations occur and on the strength of the natural selection, which is a function of how unfavourable the mutation proves to be.
A new study found that Americans 40 and older could live over five years longer if they exercised as much as the top 25% of the population. Here's what to know.