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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Tests on joint fluid may pick up on markers associated with some causes of joint pain like gout and infectious arthritis. Imaging tests. Imaging can help a healthcare provider visualize what your ...
Over time, iron stores increase, and individuals with type 4A hemochromatosis may develop hepatic fibrosis. [3] The symptoms of type 4B hemochromatosis tend to be more severe. They resemble the symptoms of hemochromatosis types 1, 2, and 3. Plasma iron concentration is elevated, and symptoms include joint pain, diabetes, and arrhythmia.
Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2] [3] In some types of arthritis, other organs are also affected. [7] Onset can be gradual or sudden. [6] There are over 100 types of arthritis.
"Repetitive impact to an injured joint can lead to long-term consequences including permanent damage to the cartilage—arthritis—or intractable pain and inflammation," Dr. Zarin explains. It's ...
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A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Here are ways to treat the pain. Many people experience aches in their knees, hips, and lower backs. Here are ways to treat the pain. Skip to main content. 24/7 Help. For premium support please ...
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