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2. Mycophenolic acid - Wikipedia

   en.wikipedia.org/wiki/Mycophenolic_acid

   Mycophenolate mofetil, a prodrug form of mycophenolic acid used in medicine. Mycophenolate mofetil is the morpholino‌ ethyl ester of mycophenolic acid; the ester masks the carboxyl group. [42] Mycophenolate mofetil is reported to have a pKa values of 5.6 for the morpholino moiety and 8.5 for the phenolic group.

3. Chronic inflammatory demyelinating polyneuropathy - Wikipedia

   en.wikipedia.org/wiki/Chronic_inflammatory_de...

   Non-cytotoxic immunosuppressive treatments usually include the anti-rejection transplant drugs azathioprine (Imuran/Azoran) and mycophenolate mofetil (Cellcept). In the U.S., these drugs are used "off-label", meaning that they do not have an indication for the treatment of CIDP in their package inserts.

4. Tolcapone - Wikipedia

   en.wikipedia.org/wiki/Tolcapone

   Tolcapone is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa or levodopa/benserazide medications. Levodopa is a prodrug for dopamine, which reduces Parkinson symptoms; carbidopa and benserazide are aromatic L-amino acid decarboxylase (AADC) inhibitors.

5. Extrapyramidal symptoms - Wikipedia

   en.wikipedia.org/wiki/Extrapyramidal_symptoms

   Although Parkinson's disease is primarily a disease of the nigrostriatal pathway and not the extrapyramidal system, loss of dopaminergic neurons in the substantia nigra leads to dysregulation of the extrapyramidal system. Since this system regulates posture and skeletal muscle tone, a result is the characteristic bradykinesia of Parkinson's.

6. Hope for Parkinson’s disease symptoms is found in ... - AOL

   www.aol.com/finance/hope-parkinson-disease...

   Parkinson’s disease, which is lifelong, progressive, and has no cure, occurs when brain cells that make dopamine, a chemical that coordinates movement, stop working or die, according to the ...

7. Biperiden - Wikipedia

   en.wikipedia.org/wiki/Biperiden

   Biperiden may lower the seizure-threshold. Some instances of dementia have been noted to correlate with chronic administration of anticholinergic medications such as biperiden for Parkinson's disease. [13] Peripheral side effects : Blurred vision, dry mouth, impaired sweating, abdominal discomfort, and obstipation are frequent.

8. Entacapone - Wikipedia

   en.wikipedia.org/wiki/Entacapone

   Entacapone is used in addition to levodopa and carbidopa for people with Parkinson's disease to treat the signs and symptoms of end-of-dose "wearing-off." [5] "Wearing-off" is characterized by the re-appearance of both motor and non-motor symptoms of Parkinson's disease occurring towards the end of a previous levodopa and carbidopa dose. [6]

9. Catechol-O-methyltransferase inhibitor - Wikipedia

   en.wikipedia.org/wiki/Catechol-O-methyltransfer...

   COMT inhibitors are indicated for the treatment of Parkinson's disease in combination with levodopa and an aromatic L-amino acid decarboxylase inhibitor (e.g. carbidopa or benserazide). The therapeutic benefit of using a COMT inhibitor is based on its ability to prevent the methylation of levodopa to 3- O -methyldopa , thus increasing the ...