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Alpha-1 blocker, blocks alpha receptors and it relaxes the smooth muscles in the bladder. It helps the urine to flow smoothly and it can lessen the pain caused by the bladder pressing on the prostate. [44] [45] Selective alpha-1 blockers are better tolerated than non-selective alpha blockers in the body and therefore works better on BPH. [2]
When alpha blockers are used to treat BPH, it causes vasodilation of blood vessels on the bladder and the prostate, thus increasing urination in general. [32] However, these alpha blockers can produce the exact opposite side effect, in which edema, or abnormal fluid retention, occurs. [33]
Tamsulosin is an alpha blocker and works by relaxing muscles in the prostate. [10] Specifically it is an α 1-adrenergic receptor blocker. [6] Tamsulosin was approved for medical use in the United States in 1997. [6] It is available as a generic medication. [9]
The older, broadly non-selective alpha blocker medications such as phenoxybenzamine are not recommended for control of BPH. [74] Non-selective alpha blockers such as terazosin and doxazosin may also require slow dose adjustments as they can lower blood pressure and cause syncope (fainting) if the response to the medication is too strong.
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1-adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
Alpha-blockers. When taken with Cialis, alpha-blockers can cause a drop in blood pressure. These medications are frequently prescribed to manage high blood pressure, benign prostatic hyperplasia ...
It was the first alpha blocker which was used for treating Benign Prostatic Hyperplasia. [22] Another Alpha Blocker Prazosin, which was the first drug selective to alpha 1 receptor, was developed in 1987 [22] for the therapy of Benign Prostatic Hyperplasia. Other alpha blockers are then introduced for several diseases. [22]
Prazosin, sold under the brand name Minipress among others, is a medication used to treat high blood pressure, symptoms of an enlarged prostate, and nightmares related to post-traumatic stress disorder (PTSD). [6] It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and ...
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