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A diagnosis of vitamin B 12 deficiency is determined by blood levels lower than 200 or 250 picograms per ml (148 or 185 picomoles per liter). [3] Some people can have symptoms with their normal levels of the vitamin, or may have low levels despite having no symptoms. [5] Other tests may be done to ensure individuals status. [3]
Diagnosis is not always straightforward as serum levels can be falsely high or normal. [10] Elevated methylmalonic acid levels may also indicate a deficiency. [2] Individuals with low or marginal values of vitamin B 12 in the range of 148–221 pmol/L (200–300 pg/mL) may not have classic neurological or hematological signs or symptoms. [2]
This may also be called standard range. In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in ...
A vitamin B12 level of less than 200 pg/mL is considered deficient. Treatment. First, have your health care provider run blood tests to see if you truly have a B12 deficiency. If you do, the only ...
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Diagnosis is supported based on vitamin B 12 blood levels below 150–180 pmol/L (200–250 pg/mL) in adults. [51] However, serum values can be maintained while tissue B 12 stores are becoming depleted. Therefore, serum B 12 values above the cut-off point of deficiency do not necessarily confirm adequate B 12 status. [2]
Vitamin B12 deficiency symptoms . Vitamin B12 deficiency has a few hallmark symptoms, according to doctors: Lack of energy. Mental fatigue. Nausea, vomiting, or diarrhea. Lack of appetite. Weight loss
Normal serum levels may be found in cases of deficiency where myeloproliferative disorders, liver disease, transcobalamin II, or small intestinal bacterial overgrowth are present. [ 56 ] [ 57 ] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency , pregnancy , oral contraceptive use ...
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