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Triiodothyronine, also known as T 3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate. [1] Production of T 3 and its prohormone thyroxine (T 4) is activated by thyroid-stimulating hormone (TSH), which is released from the anterior ...
Thyroid hormone leads to heat generation in humans. However, the thyronamines function via some unknown mechanism to inhibit neuronal activity; this plays an important role in the hibernation cycles of mammals and the moulting behaviour of birds. One effect of administering the thyronamines is a severe drop in body temperature.
Liothyronine is the most potent form of thyroid hormone. As a salt of triiodothyronine (T 3), it is chemically similar and pharmacologically equivalent to T 3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness.
3,5-T 2 is an active thyroid hormone. It stimulates the TR-beta receptor for thyroid hormones and thus increases energy expenditure. [1] [2] It has agonistic (thyromimetic) effects at myocardial tissue and pituitary, which results in 3,5-T 2 suppressing TSH release.
Once the thyroid function is reduced, replacement hormone therapy (levothyroxine) taken orally each day replaces the thyroid hormone that is normally produced by the body. [ 46 ] There is extensive experience, over many years, of the use of radioiodine in the treatment of thyroid overactivity and this experience does not indicate any increased ...
Researchers studied over 100 volunteers between the ages of 25 and 75 who donated blood or provided biological samples every few months over nearly two years, assessing changes in over 135,000 ...
Hypothyroidism is more common in women than in men. [3] People over the age of 60 are more commonly affected. [3] Dogs are also known to develop hypothyroidism, as are cats and horses, albeit more rarely. [12] The word hypothyroidism is from Greek hypo-'reduced', thyreos 'shield', and eidos 'form', where the two latter parts refer to the ...
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