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Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
pain: Greek ἄλγος (álgos) analgesic-algia, alg(i)o-pain Greek myalgia: all-denoting something as different, or as an addition Greek ἄλλος (állos), another, other alloantigen, allopathy: ambi-denoting something as positioned on both sides; describing both of two Latin ambi-, ambo, both, on both sides ambidextrous: amnio-
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...
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In addition, there are three subtypes of μ-receptor: μ 1 and μ 2, and the newly discovered μ 3. Another receptor of clinical importance is the opioid-receptor-like receptor 1 (ORL1), which is involved in pain responses as well as having a major role in the development of tolerance to μ-opioid agonists used as analgesics.
Another problem with pain management is that pain is the body's natural way of communicating a problem. [6] Pain is supposed to resolve as the body heals itself with time and pain management. [ 6 ] Sometimes pain management covers a problem, and the patient might be less aware that they need treatment for a deeper problem.
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Sufentanil offers properties of sedation and can be used as analgesic component of anesthetic regimen during an operation. [9]Because of its extremely high potency, it is often used in surgery and post-operative pain management for patients that are heavily opioid dependent/opioid tolerant because of long term opiate use for chronic pain or illicit opiate use.