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Hepatitis A is an infectious disease of the liver caused by Hepatovirus A (HAV); [7] it is a type of viral hepatitis. [8] Many cases have few or no symptoms, especially in the young. [ 1 ] The time between infection and symptoms, in those who develop them, is two–six weeks. [ 2 ]
Hepatitis A and E are mainly spread by contaminated food and water. [3] Hepatitis B is mainly sexually transmitted, but may also be passed from mother to baby during pregnancy or childbirth and spread through infected blood. [3] Hepatitis C is commonly spread through infected blood such as may occur during needle sharing by intravenous drug ...
Hepatitis A vaccine is a vaccine that prevents hepatitis A. [2] [3] It is effective in around 95% of cases and lasts for at least twenty years and possibly a person's entire life. [4] If given, two doses are recommended beginning after the age of one. [2] It is given by injection into a muscle. [2]
The first human liver transplant was performed in 1963 by Dr. Thomas E. Starzl on a three-year-old male afflicted with biliary atresia after perfecting the technique on canine livers. [ 9 ] [ 10 ] Baruch S. Blumberg discovered hepatitis B virus in 1966 and developed the first vaccine against it 1969.
In the 1960s, the first virus that could cause hepatitis was discovered. This was hepatitis B virus, which was named after the disease it causes. [220] Hepatitis A virus was discovered in 1974. [221] The discovery of hepatitis B virus and the invention of tests to detect it have radically changed many medical, and some cosmetic procedures.
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [1] Early symptoms can include fever, dark urine, abdominal pain, and yellow tinged skin. [1]
Liver transplantation is the standard of care in people presenting with fulminant liver failure or those with the progression of disease despite multiple lines of therapy. [33] [34] [35] Many patients, once started on long-term immunosuppressive therapy, will remain on that treatment for life.
Baruch Samuel Blumberg (July 28, 1925 – April 5, 2011), known as Barry Blumberg, was an American physician, geneticist, and co-recipient of the 1976 Nobel Prize in Physiology or Medicine (with Daniel Carleton Gajdusek), for his work on the hepatitis B virus while an investigator at the NIH and at the Fox Chase Cancer Center. [3]