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  2. Lupus anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Lupus_anticoagulant

    The "lupus anticoagulant paradox" [6] may be explained by platelet activation as described above, as well as enhancement of activated protein C resistance and suppression of the anticoagulant activity of TFPIα. Another proposed mechanism is the antibody-mediated destruction of Annexin A5 on the membranes of endothelial cells and trophoblast ...

  3. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Subtypes of antinuclear antibodies include anti-Smith and anti-double stranded DNA antibodies (which are linked to SLE) and anti-histone antibodies (which are linked to drug-induced lupus). Anti-dsDNA antibodies are highly specific for SLE; they are present in 70% of cases, whereas they appear in only 0.5% of people without SLE. [13]

  4. Autoantibody - Wikipedia

    en.wikipedia.org/wiki/Autoantibody

    An autoantibody is an antibody (a type of protein) produced by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases (notably lupus erythematosus ) are associated with such antibodies.

  5. What is lupus and how is it treated? - AOL

    www.aol.com/news/lupus-treated-020821382.html

    The NHS says lupus, or systemic lupus erythematosus, is a long-term condition that subverts the immune system, causing the body’s natural defence measures to turn on healthy organs. There is ...

  6. Anti-histone antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-histone_antibodies

    Ninety-six percent of patients with lupus induced by procainamide will have a positive test for anti-histone antibodies, and 100% of patients whose lupus was induced by penicillamine, isoniazid, or methyldopa will have a positive test for anti-histone antibodies. In 70% of patients with rheumatoid arthritis, Felty's syndrome, Sjogren's syndrome ...

  7. Drug-induced lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_lupus_erythe...

    Furthermore, anti-histone antibodies can also be positive in drug-induced lupus. [citation needed] Anti-Histone antibodies are positive in up to 95% of patients with drug induced lupus. The most common medications associated with drug induced lupus are hydralazine, procainamide, isoniazid, methyldopa, chlorpromazine, quinidine, and minocycline. [9]

  8. Anti-apolipoprotein antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-Apolipoprotein_antibodies

    In autoimmune disease, anti-apolipoprotein H (AAHA) antibodies, also called anti-β 2 glycoprotein I antibodies, comprise a subset of anti-cardiolipin antibodies and lupus anticoagulant. These antibodies are involved in sclerosis and are strongly associated with thrombotic forms of lupus. [ 1 ]

  9. Lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Lupus_erythematosus

    Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .

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