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Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone . [ 8 ]
Elotuzumab, sold under the brand name Empliciti, is a humanized IgG1 monoclonal antibody medication used in combination with lenalidomide and dexamethasone, for adults that have received 1 to 3 prior therapies for the treatment of multiple myeloma. [3]
The thalidomide molecule is a synthetic derivative of glutamic acid and consists of a glutarimide ring and a phthaloyl ring (Figure 5). [15] [16] Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione and it has one chiral center [15] After thalidomide's selective inhibition of TNF-α had been reported, a renewed effort was put in thalidomide's clinical development.
Other drugs, including Revlimid, used to treat multiple myeloma, rose by 7%, to a list price of more than $89,000 per month. Black people in the U.S. are more likely to be diagnosed with the ...
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Thalidomide is a known human teratogen and carries an extremely high risk of severe, life-threatening birth defects if administered or taken during pregnancy. [6] It causes skeletal deformities such as amelia (absence of legs and/or arms), absence of bones, and phocomelia (malformation of the limbs).
A wall of wintry mix and rain was pushing into parts of the East on Sunday as a strong arctic high pressure system was forecast to help fuel snow and ice for a large part of the interior Northeast ...
KFF estimates the average out-of-pocket cost to take the cancer drug Revlimid in 2020 was $6,200, for example. Some 1.4 million Part D enrollees paid more than $2,000 for prescription drugs in ...
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