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Centrilobular emphysema, also called centriacinar emphysema, affects the centre of a pulmonary lobule (centrilobular) in the lung, the area around the terminal bronchiole and the first respiratory bronchiole, and can be seen on imaging as an area around the tip of the visible pulmonary artery.
Endobronchial valves are inserted using a bronchoscope into sections of the lungs damaged by emphysema. Endobronchial valves are medical devices that allow air to exit these sections but not to re-enter. The valves, in effect, cause damaged lung tissue to deflate, thereby reducing the excessive lung volume (hyperinflation) caused by emphysema.
COPD is generally irreversible although lung function can partially recover if the patient stops smoking. Smoking cessation is an essential aspect of treatment. [ 9 ] Pulmonary rehabilitation programmes involve intensive exercise training combined with education and are effective in improving shortness of breath.
The 2023 theme for World COPD Day is “Breathing is Life - Act Earlier”. This theme underscores the importance of early lung health, early diagnosis, and prompt interventions. COPD can start early in life, affecting young individuals, and identifying precursor conditions allows for timely treatment. [10] [11]
The importance of diagnosing respiratory compromise is that with earlier diagnosis and treatment progression to respiratory failure may be prevented. Enhanced monitoring techniques and specific therapies may prevent progression of respiratory compromise to respiratory failure and possible death.
The Buteyko method emphasizes the role of carbon dioxide and hyperventilation in respiratory diseases as well as overall health. It is known that hyperventilation can lead to low carbon dioxide levels in the blood (or hypocapnea), which can subsequently lead to disturbances of the acid-base balance in the blood and lower tissue oxygen levels.
Treatment of the underlying cause is required, if possible. The treatment of acute respiratory failure may involve medication such as bronchodilators (for airways disease), [7] [8] antibiotics (for infections), glucocorticoids (for numerous causes), diuretics (for pulmonary oedema), amongst others.
The definition of a COPD exacerbation is commonly described as "lost in translation", [9] meaning that there is no universally accepted standard with regard to defining an acute exacerbation of COPD. Many organizations consider it a priority to create such a standard, as it would be a major step forward in the diagnosis and quality of treatment ...
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