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Nicotine products like gum and mints — which some people use to help curb their addition and eventually quit smoking and vaping — are the “least harmful” way to consume nicotine, according ...
Still, if you're looking to quit smoking cigarettes, it's really best to talk to your healthcare provider about your options—and if you're not a smoker, experts advise passing on this trend.
Volunteers who had either switched to e-cigarettes or another form of nicotine-replacement therapy (NRT) for at least six months, researchers found, had much lower levels of toxins and carcinogens ...
The role of nicotine in carcinogenesis is of great importance in the evaluation of potentially harmful effects from non-tobacco related sources of nicotine, such as e-cigarettes. [204] Nicotine has been shown to induce chromosomal aberration, chromatid exchange, single-strand DNA strand breaks, and micronuclei in vitro. [204]
Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) [9] and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms.
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
A relatively new nicotine product with a tobacco-free and smokeless design has drawn in a wave of new users in just the past year: oral nicotine pouches that sit at the gums and are nearly ...
Nicotine exposure during brain development may hamper growth of neurons and brain circuits, effecting brain architecture, chemistry, and neurobehavioral activity. [1] Nicotine changes the way synapses are formed, which can harm the parts of the brain that control attention and learning. [6]