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Fever, tiredness, unspecific arthralgias, or myalgias are commonly treated with nonsteroidal anti-inflammatory medications (NSAIDs), hydroxychloroquine, or a low dose of prednisone, depending on the severity. [68] Mild joint involvement can be effectively treated with NSAIDs, hydroxychloroquine, and oral prednisone.
Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...
Ultimately, antiarthritic treatments aim to achieve disease remission or low disease activity if remission cannot be achieved and thereby improving quality of life. [8] The pharmacological effects of antiarthritic medications are typically exerted through the reduction of inflammation, suppression of the immune system and/or aid in easing pain.
Prednisone is often also prescribed as a form of treatment for sudden sensorineural hearing loss (SSNHL). [16] Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large doses of loop diuretics.
The pain medication paracetamol (acetaminophen) is the first line treatment for osteoarthritis. [61] [95] Pain relief does not differ according to dosage. [62] However, a 2015 review found acetaminophen to have only a small short-term benefit with some concerns on abnormal results for liver function test. [96]
With an estimated 52.5 million adults in the U.S. affected by arthritis alone and up to 24% of adults experiencing muscle pain during their lifetime, effective topical pain relievers can be life ...