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Gold nanoparticles in chemotherapy and radiotherapy is the use of colloidal gold in therapeutic treatments, often for cancer or arthritis. Gold nanoparticle technology shows promise in the advancement of cancer treatments. Some of the properties that gold nanoparticles possess, such as small size, non-toxicity and non-immunogenicity make these ...
Gold nanoshells, coated silica nanoparticles with a thin layer of gold. [6] have been conjugated to antibodies (anti-HER2 or anti-IgG) via PEG linkers. After incubation of SKBr3 cancer cells with the gold nanoshells, an 820 nm laser was used to irradiate the cells. Only the cells incubated with the gold nanoshells conjugated with the specific ...
Similar results have also been achieved with other types of nanoparticles, including gold-coated nanoshells and nanorods that exhibit certain degrees of 'tunability' of the absorption properties of the nanoparticles to the wavelength of light for irradiation. The success of this approach to cancer treatment rests on the existence of an 'optical ...
Gold nanoparticles (such as AuNPs) have the benefit of being biocompatible and the flexibility to have multiple different molecules, and fundamental materials, attached to their shell (almost anything that can normally be attached to gold can be attached to the gold nano-shell, which can be used in helping identifying and treating cancer).
One of many examples is the work regarding thermal ablation with gold nanoparticles. Halas, West and coworkers have shown a possible complement to radiation and chemotherapy in cancer therapy, wherein once nanoparticles are at the cancer site they can be heated up in response to a skin penetrating near IR laser (Photothermal effect).
Gold nanoparticles accumulate in tumors, due to the leakiness of tumor vasculature, and can be used as contrast agents for enhanced imaging in a time-resolved optical tomography system using short-pulse lasers for skin cancer detection in mouse model. It is found that intravenously administered spherical gold nanoparticles broadened the ...
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Kanzius RF Therapy is an experimental cancer therapy that employs a combination of either gold or carbon nanoparticles and radio waves. [2] [8] [9]The specific absorption rate for radio waves by living tissue in the proposed wavelengths and intensity levels is very low.