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Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea, vomiting, or the kidneys. [3]
A simple means of estimating renal function is to measure pH, blood urea nitrogen, creatinine, and basic electrolytes (including sodium, potassium, chloride, and bicarbonate). As the kidney is the most important organ in controlling these values, any derangement in these values could suggest renal impairment.
Bicarbonate concentration is also further regulated by renal compensation, the process by which the kidneys regulate the concentration of bicarbonate ions by secreting H + ions into the urine while, at the same time, reabsorbing HCO − 3 ions into the blood plasma, or vice versa, depending on whether the plasma pH is falling or rising ...
The protective effects on kidney health in the group consuming the diet rich in fruits and vegetables were also seen in participants who were administered an oral sodium bicarbonate tablet daily ...
Baking soda can help slow the progression of chronic kidney disease. Some research, including a 2021 review, suggests sodium bicarbonate might assist with slowing down chronic kidney disease ...
Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values. Kidneys maintain the acid-base balance through two mechanisms: (1) the secretion of H + ions into the urine (from the blood) and (2) the reabsorption of bicarbonate ...
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