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Niacin has been linked to a higher risk of heart disease. It is often added to flour and fortified cereals in the U.S. The B vitamin used to be a popular medication to lower high cholesterol.
High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research.. The report, published Monday ...
The body also converts niacin and the amino acid tryptophan into NAD, says Martens — these are both found in some foods and available as supplements, but may not be as effective.
The American Heart Association strongly advises against the substitution of dietary supplement niacin for prescription niacin because of potentially serious side effects, which means that niacin should only be used under the supervision of a health care professional, and because manufacture of dietary supplement niacin is not as well-regulated ...
Liver disease or kidney disease: Niacin can accumulate in people with liver or kidney problems, potentially worsening their condition. [ 1 ] Bleeding disorders : Inositol nicotinate may slow blood clotting, increasing the risk of bleeding for individuals with clotting disorders or those undergoing surgery.
Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a lipid-lowering agent.It reduces triglyceride levels and increases HDL cholesterol. It may have less marked adverse effects than niacin, although it is unclear whether the recommended dose is as effective as standard doses of niacin.
The HDL-Atherosclerosis Treatment Study, also known as HATS, was a three-year double-blind trial involving 160 people with coronary heart disease (CHD) who had a low HDL and near normal LDL. The study compared a combination of simvastatin and niacin with antioxidant vitamin therapy. Using angiography, coronary artery stenosis progressed when ...
Heart disease is the leading cause of death for men, women and people of most racial and ethnic groups, causing avoid complications such as heart attack, stroke and even damage to the kidney and ...