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However, across the spectrum of dosage of amoxicillin-clavulanate combination, the dose of clavulanate is constant at 125 mg, whereas the dose of amoxicillin varies at 250 mg, 500 mg and 875 mg. Thus the use of low-dose amoxicillin-clavulanate in combination with meropenem may be used in part of a treatment regimen for drug-resistant TB and ...
Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic , when combined with penicillin -group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase , which otherwise inactivates most penicillins.
[3] [41] [43] [44] Amoxicillin-induced neurotoxicity has been especially associated with concentrations of greater than 110 mg/L. [45] The onset of an allergic reaction to amoxicillin can be very sudden and intense; emergency medical attention must be sought as quickly as possible. The initial phase of such a reaction often starts with a change ...
Amoxicillin: Novamox, Amoxil: Wide range of infections; penicillin used for streptococcal infections, syphilis, and Lyme disease: Gastrointestinal upset and diarrhea; Allergy with serious anaphylactic reactions; Brain and kidney damage (rare)
A new antibiotic is effective against gonorrhea symptoms, easing fears about the rise in drug-resistant strains of the sexually transmitted infection.
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In addition to combining one antibiotic with another, antibiotics are sometimes co-administered with resistance-modifying agents. For example, β-lactam antibiotics may be used in combination with β-lactamase inhibitors, such as clavulanic acid or sulbactam, when a patient is infected with a β-lactamase-producing strain of bacteria. [75]
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