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Estriol (E3), sold under the brand name Ovestin among others, is an estrogen medication and naturally occurring steroid hormone which is used in menopausal hormone therapy. [12] [4] [6] [13] It is also used in veterinary medicine as Incurin to treat urinary incontinence due to estrogen deficiency in dogs.
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For comparison, the metabolic clearance rate of estriol is 1,110 L/day/m 2. [5] A single 1 to 2 mg dose of estrone in oil solution by intramuscular injection has a duration of about 2 or 3 days. [ 45 ] [ 67 ] [ 68 ] As an aqueous suspension by intramuscular injection , estrone was used at a dose of 0.1 to 0.5 mg 2 to 3 times per week, or at a ...
Estriol succinate, also known as estriol disuccinate or as estriol 16α,17β-di(hydrogen succinate), is a synthetic estrane steroid and a derivative of estriol. [7] [29] [30] It is specifically the C16α and C17β disuccinate ester of estriol. [7] [29] [30] [1] The medication is provided both as estriol succinate and as estriol sodium succinate ...
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. [1] [2] It is one of three major endogenous estrogens, the others ...
[11] [154] Given by subcutaneous injection in mice, estradiol is about 10-fold more potent than estrone and about 100-fold more potent than estriol. [ 154 ] The ERs are expressed widely throughout the body, including in the breasts , uterus , vagina , fat , skin , bone , liver , pituitary gland , hypothalamus , and other parts of the brain . [ 27 ]
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