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[5] [6] [7] When researching a new compound, Giurgea found a spectrum of effects that did not align with any psychotropic drug category, leading to his proposal of a new category and the concept of the term nootropic. [6] Giurgea stated that nootropic drugs should have the following characteristics: They should enhance learning and memory.
The hippocampus regulates memory function. Memory improvement is the act of enhancing one's memory. Factors motivating research on improving memory include conditions such as amnesia, age-related memory loss, people’s desire to enhance their memory, and the search to determine factors that impact memory and cognition.
Approved for treating narcolepsy, obstructive sleep apnea, and shift work sleep disorder, modafinil is a wakefulness-promoting drug used to decrease fatigue, increase vigilance, and reduce daytime sleepiness. [1] Modafinil improves alertness, attention, long-term memory, and daily performance in people with sleep disorders. [1] [18]
The temporal differentiation between early and late LTP is also based on this. Early LTP is associated with short-term memory and late LTP with long-term memory. Behavioural studies raised evidence against this differentiation. Studies with protein synthesis inhibitors showed that blocking protein synthesis did not block memory retention. [19]
Drugs such as amphetamine and methylphenidate increase power output at constant levels of perceived exertion and delay the onset of fatigue, [18] [19] [23] among other athletic-performance-enhancing effects; [3] [14] [15] bupropion also increases power output at constant levels of perceived exertion, but only during short-term use. [23]
The former Big Brother presenter has had surgery to remove a colloid cyst, a type of rare fluid-filled benign tumour in the brain.
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