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Inside of a bone showing the trabecular structure A typical carcinoid tumor of the lung showing a trabecular pattern of elongated groups of cells.. A trabecula (pl.: trabeculae, from Latin for 'small beam') is a small, often microscopic, tissue element in the form of a small beam, strut or rod that supports or anchors a framework of parts within a body or organ.
These areas rely on the trabecular bone for strength, so the intense remodeling causes these areas to degenerate most when the remodeling is imbalanced. [citation needed] Around the ages of 30–35, cancellous or trabecular bone loss begins. Women may lose as much as 50%, while men lose about 30%. [38]
The trabecular bone score is a measure of bone texture correlated with bone microarchitecture and a marker for the risk of osteoporosis. Introduced in 2008, [ 1 ] its main projected use is alongside measures of bone density in better predicting fracture risk in people with metabolic bone problems.
Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. [1] [2] It can manifest in localized or generalized osteosclerosis.
Trabecular edema, also known as bone marrow edema (BME), is a traditional term describing the interstitial fluid accumulation at the trabecular bone marrow. The term was first used in 1988, [1] referring to the changes in the bone marrow due to inflammation. [3]
The osteoblasts form new lamellar bone upon the recently exposed surface of the mineralized matrix. This new lamellar bone is in the form of trabecular bone. Eventually, all of the woven bone and cartilage of the original fracture callus is replaced by trabecular bone, restoring most of the bone's original strength. [citation needed]
The trabecular bone has much higher metabolic activity than the cortical bone and so is affected by age, disease and therapy-related changes earlier and to a greater degree than cortical bone. This means that QCT of the spine has an advantage compared to other bone density tests because earlier changes in bone mineral density may be detected . [1]
DEXA assessment of bone mineral density of the femoral neck (A) and the lumbar spine (B): T scores of - 4.2 and - 4.3 were found at the hip (A) and lumbar spine (B), respectively in a 53-year-old male patient affected with Fabry disease. The World Health Organization has defined the following categories based on bone density in white women: