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  2. Cholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_inhibitor

    Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.

  3. Donepezil - Wikipedia

    en.wikipedia.org/wiki/Donepezil

    Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [3] [4] [8] It appears to result in a small benefit in mental function and ability to function. [9] Use, however, has not been shown to change the progression of the disease. [10] Treatment should be stopped if no benefit ...

  4. Benzgalantamine - Wikipedia

    en.wikipedia.org/wiki/Benzgalantamine

    Benzgalantamine is a prodrug of galantamine. [1] The most common side effects include nausea, vomiting, diarrhea, dizziness, headache, and decreased appetite. [1] Benzgalantamine was approved for medical use in the United States in July 2024. [1] [2] [3]

  5. Motivation-enhancing drug - Wikipedia

    en.wikipedia.org/wiki/Motivation-enhancing_drug

    Acetylcholinesterase inhibitors, like donepezil, rivastigmine, and galantamine, have been used in the treatment of disorders of diminished motivation. [ 17 ] [ 18 ] [ 6 ] [ 11 ] These drugs inhibit acetylcholinesterase , which metabolizes the neurotransmitter acetylcholine , thereby increasing acetylcholine levels in the brain and augmenting ...

  6. Galantamine - Wikipedia

    en.wikipedia.org/wiki/Galantamine

    Galantamine is a type of acetylcholinesterase inhibitor.It is an alkaloid extracted from the bulbs and flowers of Galanthus nivalis (common snowdrop), Galanthus caucasicus (Caucasian snowdrop), Galanthus woronowii (Voronov's snowdrop), and other members of the family Amaryllidaceae, such as Narcissus (), Leucojum aestivum (snowflake), and Lycoris including Lycoris radiata (red spider lily). [5]

  7. Acetylcholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Acetylcholinesterase_inhibitor

    Acetylcholine Acetylcholinesterase Acetylcholinesterase inhibition. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ...

  8. Memantine - Wikipedia

    en.wikipedia.org/wiki/Memantine

    Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. [24] The UK National Institute for Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia.

  9. Rivastigmine - Wikipedia

    en.wikipedia.org/wiki/Rivastigmine

    Usage of rivastigmine was associated with a higher frequency of reports of death as an adverse event in the Food and Drug Administration Adverse Event Reporting System database compared to the other acetylcholinesterase inhibiting drugs donepezil and galantamine; this increase could be related to improper application of the transdermal patch ...

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