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779.2 Cerebral depression coma and other abnormal cerebral signs in fetus or newborn; 779.3 Feeding problems in newborn. 779.31 Feeding problems in newborn; 779.32 Bilious vomiting in newborn; 779.33 Other vomiting in newborn; 779.34 Failure to thrive in newborn; 779.4 Drug reactions and intoxications specific to newborn; 779.5 Drug withdrawal ...
Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [ 1 ]
Physiologic jaundice can be a benign condition that presents in newborns until two weeks of life. [2] However, jaundice that continues after two weeks requires follow up with measurement of total and conjugated bilirubin. [3] Elevated levels of conjugated bilirubin are never benign and require further evaluation for neonatal cholestasis. [3]
In undiagnosed and untreated children, the accumulation of precursor metabolites due to the deficient activity of galactose 1-phosphate uridylyltransferase (GALT) can lead to feeding problems, failure to thrive, liver damage, bleeding, and infections. The first presenting symptom in an infant is often prolonged jaundice.
Onset of breast milk jaundice is within 2 weeks after birth and lasts for 4–13 weeks. [citation needed] While most cases of newborn jaundice are not harmful, when bilirubin levels are very high, brain damage—kernicterus—may occur [55] [8] leading to significant disability. [56]
Cessation of breastfeeding before the mother had planned to stop, usually as a result of breastfeeding difficulties; Low milk supply in general; Inability to establish breastfeeding, which may be caused by delayed onset of lactation; Lactation failure can result in neonatal jaundice. [1]
Breast milk jaundice is jaundice that persists despite appropriate weight gain. [40] This type of jaundice may start as breastfeeding jaundice and persist, or may not appear until after the baby has begun to gain weight, typically around 4–5 days old. [10]: 34–47 [40] It often persists beyond the second and third weeks of life. [40]
Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]