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In immunology, seroconversion is the development of specific antibodies in the blood serum as a result of infection or immunization, including vaccination. [1] [2] ...
Main symptoms of acute HIV infection. Acute HIV infection, primary HIV infection or acute seroconversion syndrome [1]: 416 is the first stage of HIV infection. It occurs after the incubation stage, before the latency stage, and the potential AIDS succeeding the latency stage.
Antibody tests may give false negative (no antibodies were detected despite the presence of HIV) results during the window period, hence an interval of three weeks to six months between the time of HIV exposure and the production of measurable antibodies to HIV seroconversion is implemented. Most people develop detectable antibodies ...
In antibody-based testing, the window period is dependent on the time taken for seroconversion. The window period is important to epidemiology and safe sex strategies, and in blood and organ donation, because during this time, an infected person or animal cannot be detected as infected but may still be able to infect others. For this reason ...
This page was last edited on 15 March 2006, at 00:53 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
This acute viremia is associated in virtually all people with the activation of CD8 + T cells, which kill HIV-infected cells, and subsequently with antibody production, or seroconversion. The CD8 + T cell response is thought to be important in controlling virus levels, which peak and then decline, as the CD4 + T cell counts rebound.
At this point, seroconversion, the development of antibodies, occurs and the CD4 T cell counts begin to recover as the immune system attempts to fight the virus, marking the HIV set point. The higher the viral load at the set point, the faster the virus will progress to AIDS ; the lower the viral load at the set point, the longer the patient ...
Diagnosis of primary HIV before seroconversion is done by measuring HIV-RNA or p24 antigen. [32] Positive results obtained by antibody or PCR testing are confirmed either by a different antibody or by PCR. [30] Antibody tests in children younger than 18 months are typically inaccurate, due to the continued presence of maternal antibodies. [113]