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Species of origin is designated with a three-letter prefix, e.g., hsa-miR-124 is a human (Homo sapiens) miRNA and oar-miR-124 is a sheep (Ovis aries) miRNA. Other common prefixes include "v" for viral (miRNA encoded by a viral genome) and "d" for Drosophila miRNA (a fruit fly commonly studied in genetic research).
Function Distribution Ref. Antisense RNA: aRNA, asRNA: Transcriptional attenuation / mRNA degradation / mRNA stabilisation / Translation block: All organisms [11] [12] Cis-natural antisense transcript: cis-NAT Gene regulation: CRISPR RNA: crRNA: Resistance to parasites, by targeting their DNA: Bacteria and archaea [13] Long noncoding RNA: lncRNA
let-7 was later identified in humans as the first human miRNA , and is highly conserved across many species. [3] [4] Dysregulation of let-7 contributes to cancer development in humans by preventing differentiation of cells, leaving them stuck in a stem-cell like state. [1] let-7 is therefore classified as a tumor suppressor.
n/a Ensembl ENSG00000207757 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 7: 100.09 – 100.09 Mb n/a PubMed search n/a Wikidata View/Edit Human MicroRNA 93 is a functional RNA and a microRNA that in humans is encoded by the MIR93 gene. Function The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70 ...
n/a Ensembl ENSG00000199038 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 11: 0.57 – 0.57 Mb n/a PubMed search n/a Wikidata View/Edit Human MicroRNA 210 is a protein that in humans is encoded by the MIR210 gene. Function MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in ...
A database of inverse miRNA target predictions, based on the RepTar algorithm that is independent of evolutionary conservation considerations and is not limited to seed pairing sites. database: website [17] RNA22: The first link (predictions) provides RNA22 predictions for all protein coding transcripts in human, mouse, roundworm, and fruit fly.
n/a Ensembl ENSG00000284357 n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 1: 9.15 – 9.15 Mb n/a PubMed search n/a Wikidata View/Edit Human MicroRNA 34a (miR-34a) is a microRNA that in humans is encoded by the MIR34A gene. Function microRNAs (miRNAs) are short (20–24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene ...
[3] miR-122 expression increases during embryogenesis until it constitutes 72% of total miRNA in adult human liver, making it one of the most highly expressed miRNAs in any tissue. [4] In humans, miR-122 is encoded at a single genomic locus in chromosome 18. The primary miR-122 transcript (pri-miR-122) is a long non-coding RNA.