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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, along with numerous other biological functions. [1] [2] In humans, the most significant compounds within this group are vitamin D 3 (cholecalciferol) and vitamin D 2 (ergocalciferol). [2] [3]
In medical practice, a blood test for 25-hydroxy-vitamin D, 25(OH)D, is used to determine an individual's vitamin D status. [11] The name 25(OH)D refers to any combination of calcifediol (25-hydroxy-cholecalciferol), derived from vitamin D 3, and ercalcidiol (25-hydroxy-ergocalciferol), [1] derived from vitamin D 2. The first of these (also ...
Vitamin D deficiency; Other names: ... (OH)D is the laboratory test ordered to indicate whether or not a person has vitamin D deficiency or insufficiency. [53]
The 25-hydroxy vitamin D test segment dominated the market and accounted for the largest vitamin D testing market share in 2023. The 25-hydroxy vitamin D test is the most reliable method to measure the levels of vitamin D. The body's level of vitamin D can be determined accurately by the measurement of 25-hydroxyvitamin D content in the blood.
The glucose test in particular helps screen for diabetes mellitus and pre-diabetes. The calcium test can indicate or monitor bone diseases or diseases of the parathyroid gland or kidneys. Calcium salts, lithium, thiazide diuretics, thyroxine, and vitamin D can all increase levels and may interfere with this test. [2] Serum glucose; Calcium
The 1-hydroxy group is in the alpha position, and this may be specified in the name, for instance in the abbreviation 1α,25-(OH) 2 D 3. [6] Calcitriol is, strictly, the 1-hydroxylation product of calcifediol (25-OH vitamin D 3), derived from cholecalciferol (vitamin D 3), rather than the product of hydroxylations of ergocalciferol (vitamin D 2).
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