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Vitamin B12 can be found in multivitamins, B-complex supplements, and by itself in a B12 supplement, which are available in many natural and synthetic forms including cyanocobalamin and ...
Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia.
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Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [150] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
Vitamin B 12 is derived from a tetrapyrrolic structural framework created by the enzymes deaminase and cosynthetase which transform aminolevulinic acid via porphobilinogen and hydroxymethylbilane to uroporphyrinogen III. The latter is the first macrocyclic intermediate common to heme, chlorophyll, siroheme and B 12 itself.
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