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Colchicine, a prescription medication that can ease gout pain Corticosteroids, prescription medications that can quickly reduce inflammation in the body Home remedies can also help during a gout ...
For treating gout, the initial effects of colchicine occur in a window of 12 to 24 hours, with a peak within 48 to 72 hours. [25] It has a narrow therapeutic window, requiring monitoring of the subject for potential toxicity. [25] Colchicine is not a general pain-relief drug, and is not used to treat pain in other disorders. [25]
Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...
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Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...
Confusion remains whether colchicine by itself is effective or even needed daily until a flare occurs, or whether the effective regimen requires both allopurinol and colchicine. Practically speaking, the pre-gout "alert" pain is characteristic and predictable of an onset, so why would daily dosing over a long term be needed?
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