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Liposomes were first reported as drug-delivery vehicles in the 1960s and are biomimetic nanosomes composed of phospholipid bilayers. Due to their biocompatibility, biodegradability, and ability to encapsulate both hydrophilic and hydrophobic drugs, liposomes are a popular choice for pH-responsive tumor-targeted drug delivery.
A modified nanoparticle with siRNA is now being researched and has been shown to effectively shut down the expression of gro-α. They are modified with FSH β which has a high selectivity for FSHR-positive ovarian cancer cells. The nanoparticles are aiding in delivery of the siRNA to the correct place, giving them a high selective toxicity. [2]
Other potential applications of magnetic nanoparticles are brain imaging and drug delivery past the blood-brain barrier (BBB) using biodegradable magnetic iron oxide nanoparticles. The scope of this application is the treatment of central nervous system (CNS) disorders by functioning as contrast agents and drug carriers.
This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle-mediated drug delivery in order to combat the downfalls of conventional drug delivery. These nanoparticles would be loaded with drugs and targeted to specific parts of the body where there is solely diseased tissue, thereby avoiding interaction with ...
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...
In photothermal cancer therapy, many gold nanoparticle molecules are used in each test and they must all be uniform in size. Including PEG coating, the nanoparticles measured to be ~130 nm in diameter. [1] Gold nanoparticles that act as drug delivery systems in conjugation with chemotherapeutic drugs typically range in size from 10 to 100 nm. [2]
Nanomedicine refers to the use of nanoscale materials for medical applications. In theranostics, nanomedicine offers opportunities for targeted drug delivery, imaging, and therapy. [7] Nanoparticles can be engineered to carry therapeutic payloads, imaging agents, and targeting ligands, allowing for multimodal theranostic approaches. These ...
Liposomal medicine research for cancer therapy has increased over the years as an alternative to conventional cancer treatment. [15] There is an interest in liposomal medicine because it features targeted drug delivery while mitigating the damage to healthy cells and tissues. [15]
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