Search results
Results from the WOW.Com Content Network
The Human Protein Atlas contains information about the human proteins in cells, tissues, and organs. All the data in the knowledge resource is open access to allow scientists both in academia and industry to freely access the data for exploration of the human proteome.
Proteogenomics uses an integrated approach by combining genomics, proteomics, and transcriptomics.. Proteogenomics is a field of biological research that utilizes a combination of proteomics, genomics, and transcriptomics to aid in the discovery and identification of peptides.
The human interactome is the set of protein–protein interactions (the interactome) that occur in human cells. [ 1 ] [ 2 ] The sequencing of reference genomes, in particular the Human Genome Project , has revolutionized human genetics , molecular biology , and clinical medicine .
The Human Proteome Project [1] (HPP) is a collaborative effort coordinated by the Human Proteome Organization. [2] Its stated goal is to experimentally observe all of the proteins produced by the sequences translated from the human genome .
Human Proteinpedia, which is closely associated with Institute of Bioinformatics (IOB), Bangalore and Johns Hopkins University, is a portal for sharing and integration of human proteomic data. [ 1 ] [ 2 ] It allows research laboratories to contribute and maintain protein annotations.
A list of human candidate ITIM-containing proteins has been generated by proteome-wide scans. [5] It has included more than 135 proteins with ITIM motif. This list is reportedly expanded by studying rare human SNPs that create the consensus signature S/I/V/LxYxxI/V/L motif. [6]
[8] [9] [18] There are only two human ubiquitin-activating enzymes, UBA1 and UBA6, and thus UBA1 is largely responsible for protein ubiquitination in humans. [8] [9] [18] Through its central role in ubiquitination, UBA1 has been linked to cell cycle regulation, endocytosis, signal transduction, apoptosis, DNA damage repair, and transcriptional ...
N-terminal acetylation is the protein modification that occurs on the α-amino acid group at the N-termini of proteins. The backbone amino group on the first amino acid (α-amino group) on a protein N-terminus gets an acetyl group (-COCH 3) via acetyl-CoA, and this process is catalyzed by enzymes called N-terminal acetyltransferases (NATs). [1]