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Viral load monitoring is used by HIV-positive people to develop a plan for their personal treatment of HIV/AIDS. [1] A count of the viral load is routine before the start of HIV treatment. [1] If the treatment is not changed, then viral load is monitored with testing every 3–4 months to confirm a stable low viral load. [1]
Suppressing the viral load to undetectable levels (<50 copies per ml) is the primary goal of ART. [56] This should happen by 24 weeks after starting combination therapy. [83] Viral load monitoring is the most important predictor of response to treatment with ART. [84] Lack of viral load suppression on ART is termed virologic failure.
The campaign seeks to spread the scientific evidence that undetectable means untransmittable. Since the beginning of the epidemic, perceptions and management of HIV infection have gone through many stages; from assuming the infectiousness, then discovering the routes of transmission (blood, sexual fluids, and breastfeeding), to prevention methods (education, condoms, PrEP, and PEP) and various ...
Virological failure is defined as the failure to meet a specific target of antiviral drug treatment, namely the non-attainment or non-maintenance of undetectable viral load, particularly in the treatment of HIV. As antiretroviral therapy is evaluated by detecting the amount of copies of the virus in blood samples, the concept of virological ...
A 2010 review study by Puren et al. [2] categorizes viral load testing into three types: (1) nucleic acid amplification based tests (NATs or NAATs) commercially available in the United States with Food and Drug Administration (FDA) approval, or on the market in the European Economic Area (EEA) with the CE marking; (2) "Home–brew" or in-house NATs; (3) non-nucleic acid-based test.
If a person’s viral load is so low that a standard lab can’t detect it, this is called having an undetectable viral load, HIV.gov explains. The image seemingly showed that drug users dabbed ...
The eclipse period is a variable period starting from HIV exposure in which no existing test can detect HIV. The median duration of the eclipse period in one study was 11.5 days. The window period is the time between HIV exposure and when an antibody or antigen test can detect HIV. The median window period for antibody/antigen testing is 18 days.
Long-term nonprogressors typically have viral loads under 10,000 copies /mL blood, [3] do not take antiretrovirals, and have CD4+ counts within the normal range. [4] Most people with HIV not on medication have viral loads which are much higher. It is estimated that around 1 in 500 people with HIV are long-term nonprogressors. [5]