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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
An FDA-approved weight loss medication, naltrexone-bupropion is generally considered effective and safe to use. You may experience side effects like dizziness, mood changes, trouble sleeping, and ...
The cost of injectable weight loss drugs without insurance depends on which weight loss drug you go for and where you purchase it from. But you can generally expect to pay about $1,000 to $2,000 a ...
One analysis of these same clinical trials reported the overall average weight loss on naltrexone/bupropion to be a little over 4% ... Review the prescribing information for any weight loss pill ...
Naltrexone/bupropion is indicated, as an adjunct to a reduced-calorie diet and increased physical activity, as anti-obesity medication for the management of weight in adults with an initial body mass index (BMI) of: [4] [5] 30 kg/m 2 (obese), or [4] [5]
It has also been studied for obesity [37] with significant positive effects on body weight loss and there are three ongoing clinical trials for this indication. [38] [39] [40] It was to be sold, when combined with bupropion, under the brand name Empatic, until its development was discontinued. [41]
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