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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
An FDA-approved weight loss medication, naltrexone-bupropion is generally considered effective and safe to use. You may experience side effects like dizziness, mood changes, trouble sleeping, and ...
The cost of weight loss drugs typically ranges from about $200 to $2,000 per month, depending on which type of weight loss drug you get and where you get it from. You may be eligible for insurance ...
Naltrexone/bupropion is indicated, as an adjunct to a reduced-calorie diet and increased physical activity, as anti-obesity medication for the management of weight in adults with an initial body mass index (BMI) of: [4] [5] 30 kg/m 2 (obese), or [4] [5]
It has also been studied for obesity [37] with significant positive effects on body weight loss and there are three ongoing clinical trials for this indication. [38] [39] [40] It was to be sold, when combined with bupropion, under the brand name Empatic, until its development was discontinued. [41]
There are several FDA-approved weight loss drugs, including semaglutide, orlistat, phentermine-topiramate, naltrexone-bupropion and liraglutide. Metformin is another common medication used off ...
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