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Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder .
In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]
The maker of Robitussin cough syrup is recalling several lots of products containing honey due to contamination that could pose a serious risk to people with weakened immune systems. Haleon’s ...
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
The settlement covers Robitussin purchasers from Feb. 16, 2016 to the present. Payouts may total $1.50 to $4.75 per claim, depending on the number of claims. As much as $2.05 million, or 46% of ...
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
However, in children, it has not been found to be effective. [12] Codeine was once viewed as the "gold standard" in cough suppressants, but this position is now questioned. [13] Some placebo-controlled trials have found that it is ineffective against some forms of cough, including acute cough in children. [14] [15] It is thus not recommended ...
double strength d.t.d. dentur tales doses: give of such doses DTO deodorized tincture of opium can easily be confused with "diluted tincture of opium," which is 1/25th the strength of deodorized tincture of opium; deaths have resulted due to massive morphine overdose. [9] Compare laudanum and paregoric. DW distilled water [or]
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