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  2. Work-up - Wikipedia

    en.wikipedia.org/wiki/Work-up

    The product is isolated from the mixture by the following work-up: [3] Synthesis of 4-methylcyclohexene with work-up step in red. A concentrated solution of sodium chloride in water, known as a brine solution, is added to the mixture and the layers are allowed to separate. The brine is used to remove any acid or water from the organic layer.

  3. List of unsolved problems in chemistry - Wikipedia

    en.wikipedia.org/wiki/List_of_unsolved_problems...

    This is a list of unsolved problems in chemistry. Problems in chemistry are considered unsolved when an expert in the field considers it unsolved or when several experts in the field disagree about a solution to a problem.

  4. Nucleophilic addition - Wikipedia

    en.wikipedia.org/wiki/Nucleophilic_addition

    This occurs through the formation of a covalent bond between X and one carbon atom, concomitant with the transfer of electron density from the pi bond onto the other carbon atom (step 1). [1] During a telescoped second reaction or workup (step 2), the resulting negatively charged carbanion combines with an electrophilic Y to form the second ...

  5. Acid–base extraction - Wikipedia

    en.wikipedia.org/wiki/Acid–base_extraction

    Acid–base extraction is a subclass of liquid–liquid extractions and involves the separation of chemical species from other acidic or basic compounds. [1] It is typically performed during the work-up step following a chemical synthesis to purify crude compounds [2] and results in the product being largely free of acidic or basic impurities.

  6. Silylation - Wikipedia

    en.wikipedia.org/wiki/Silylation

    The protection mechanism begins with the base deprotonating the alcohol group. Next, the deprotonated alcohol group attacks the silyl atom of the silyl halide compound. The halide acts as a leaving group and ends up in solution. A workup step follows to remove any excess base within the solution. The overall reaction scheme is as follows:

  7. Stetter reaction - Wikipedia

    en.wikipedia.org/wiki/Stetter_reaction

    The Stetter reaction is a reaction used in organic chemistry to form carbon-carbon bonds through a 1,4-addition reaction utilizing a nucleophilic catalyst. [1] While the related 1,2-addition reaction, the benzoin condensation, was known since the 1830s, the Stetter reaction was not reported until 1973 by Dr. Hermann Stetter. [2]

  8. Donald Trump mocked Canadian Prime Minister Justin Trudeau over his top minister’s surprise resignation — after the pair clashed on how to handle the president-elect’s looming tariffs.

  9. Retrosynthetic analysis - Wikipedia

    en.wikipedia.org/wiki/Retrosynthetic_analysis

    Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents. Each precursor material is examined using the same method.

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    related to: work up step organic chemistry practice problems michigan state department
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