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Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists [2] are a group of medications that disrupt the movement of calcium (Ca 2+ ) through calcium channels . [ 3 ] Calcium channel blockers are used as antihypertensive drugs , i.e., as medications to decrease blood pressure in patients with hypertension .
ATC code C08 Calcium channel blockers is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup C08 is part of the anatomical group C Cardiovascular system ...
N-type calcium channels are categorized as high threshold-activated channels and seen in the Cav2 gene family. The structure of the N-type calcium channel is very similar to other voltage-dependent channels. The most important part of the channel is the actual pore that is formed by the α1B subunit.
Calcium channel blockers. As the name suggests, these medications block calcium from entering your heart’s cells and arteries. This can relax and open up your blood vessels.
Class IV agents are slow non-dihydropyridine calcium channel blockers. They decrease conduction through the AV node , and shorten phase two (the plateau) of the cardiac action potential . They thus reduce the contractility of the heart, so may be inappropriate in heart failure.
Pages in category "Calcium channel blockers" The following 100 pages are in this category, out of 100 total. This list may not reflect recent changes. ...
7 Calcium channel blockers. 8 Antimineralocorticoid. 9 Antiplatelet drug. 10 Anticoagulant. 11 Fibrinolytics. 12 Diuretics. 13 References. Toggle the table of contents.
Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Ca v 1.3) is a protein that in humans is encoded by the CACNA1D gene. [5] Ca v 1.3 channels belong to the Ca v 1 family, which form L-type calcium currents and are sensitive to selective inhibition by dihydropyridines (DHP).