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The skin is from a person with systemic lupus erythematosus and shows IgG deposits at two different places: The first is a bandlike deposit along the epidermal basement membrane ("lupus band test" is positive); the second is within the nuclei of the epidermal cells (antinuclear antibodies are present).
Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [1]
Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]
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Russell's viper, Daboia russelii Dilute Russell's viper venom time (dRVVT) is a laboratory test often used for detection of lupus anticoagulant (LA). It is an assessment of the time for blood to clot in the presence of a diluted amount of venom from Russell's viper (Daboia russelii), a highly venomous snake native to the Indian subcontinent and named after the herpetologist Patrick Russell.
Toni Braxton is opening up about her decade-long journey to receiving a lupus diagnosis. During an episode of the SHE MD Podcast, Toni, who was diagnosed with lupus in 2008, joined co-host Mary ...
Halsey has disclosed her recent health conditions. "In 2022, I was first diagnosed with Lupus SLE and then a rare T-cell lymphoproliferative disorder,” Halsey, 29, wrote via Instagram on ...
When there is doubt about the diagnosis, a skin biopsy combined with a confirmatory histopathologic examination is recommended. Anti-SSA/Ro and anti-SSB/La laboratory studies are also recommended. In cases where histopathology is unclear, direct immunofluorescence can be utilized to help confirm the diagnosis
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