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Hereditary spastic paraplegia (HSP) is a group of inherited diseases whose main feature is a progressive gait disorder. The disease presents with progressive stiffness ( spasticity ) and contraction in the lower limbs. [ 1 ]
Paraplegia, or paraparesis, is an impairment in motor or sensory function of the lower extremities. The word comes from Ionic Greek ( παραπληγίη ) "half-stricken". [ citation needed ] It is usually caused by spinal cord injury or a congenital condition that affects the neural (brain) elements of the spinal canal .
L1 syndrome is a group of mild to severe X-linked recessive disorders that share a common genetic basis. The spectrum of L1 syndrome disorders includes X-linked complicated corpus callosum dysgenesis, spastic paraplegia 1, MASA syndrome, and X-linked hydrocephalus with stenosis of the aqueduct of Sylvius (HSAS).
In a Switzerland study, two people with spinal cord injuries received deep brain stimulation therapy and were able to walk without assistance and even climb stairs.
The average life expectancy in the U.S. is 77.5 years, according to the Centers for Disease Control and Prevention. But Americans outlive their health spans by 12.4 years, the study found. It’s ...
Life expectancy in the U.S. is projected to increase from 78.3 years in 2022 to 79.9 years in 2035 and to 80.4 years in 2050 for all sexes combined, researchers said.
This is especially true for Healthy life expectancy, the definition of which criteria may change over time, even within a country. For example, Canada is a country with a fairly high overall life expectancy at 81.63 years; however, this number decreases to 75.5 years for Indigenous people in the country. [4]
The life expectancy in some states has fallen in recent years; for example, Maine's life expectancy in 2010 was 79.1 years, and in 2018 it was 78.7 years. The Washington Post noted in November 2018 that overall life expectancy in the United States was declining although in 2018 life expectancy had a slight increase of 0.1 and bringing it to ...