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The phase III trial for approval was published in 2000 as an industry-funded randomized, placebo-controlled trial (PCT). Its authors found 1 mg alosetron, taken orally twice daily for 12 weeks, was associated with a 12% (CI 4.7-19.2) improvement in relief from abdominal pain and discomfort associated with diarrhea-predominant patients. [4]
Social media started in the mid-1990s with the invention of platforms like GeoCities, Classmates.com, and SixDegrees.com. [20] While instant messaging and chat clients existed at the time, SixDegrees was unique as it was the first online service designed for people to connect using their actual names instead of anonymously.
Linda Marie McMahon (/ m ə k ˈ m æ n /; née Edwards; born October 4, 1948) is an American politician, business executive, and former professional wrestling performer. She was the 25th administrator of the Small Business Administration from 2017 to 2019.
On 20 February, a protest was held at Vukov Spomenik in Belgrade, where 15 minutes of silence was observed. [391] The gathering, which was organized by citizens from the municipalities of Stari Grad, Savski Venac, Palilula, Zvezdara, and Vračar, as well as by the organization "Ustala je Ustanička," [ 392 ] was attended by nearly 14,000 ...
[7] [8] As a result of the latter, several commentators have warned of an unprecedented economic collapse in Russia's future, citing a 30% drop in the ruble's value, a 20% rise in interest rates and a 1% GDP expansion down from 1.7%. [9] Analyses by multiple firms project year end GDP contraction of at least 5% and inflation of 15%. [10]
Generation Z (often shortened to Gen Z), also known as Zoomers, [1] [2] [3] is the demographic cohort succeeding Millennials and preceding Generation Alpha.Researchers and popular media use the mid-to-late 1990s as starting birth years and the early 2010s as ending birth years, with the generation most frequently being defined as people born from 1997 to 2012.
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