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A box of Lorazepam Orion (Lorazepam) tablets. Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. [14] It is used to treat anxiety (including anxiety disorders), trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. [14]
In terms of the mechanism of action of benzodiazepines, their similarities are too great to separate them into individual categories such as anxiolytic or hypnotic. For example, a hypnotic administered in low doses produces anxiety-relieving effects, whereas a benzodiazepine marketed as an anti-anxiety drug at higher doses induces sleep. [175]
Several efficient benzodiazepines offer choices about dosage form, length of action, metabolic interaction and safety. Benzodiazepines function by binding to the benzodiazepine site on most, but not all, GABA A receptors. GABA A modulation by benzodiazepine site agonists is self-limiting. The channel conductance is not higher in the presence of ...
Mechanism of action [ edit ] Loprazolam is a benzodiazepine, which acts via positively modulating the GABA A receptor complex via a binding to the benzodiazepine receptor which is situated on alpha subunit containing GABA A receptors.
All sedative-hypnotics, e.g. alcohol, barbiturates, benzodiazepines and Z-drugs have a similar mechanism of action, working on the GABA A receptor complex and are cross tolerant with each other and also have abuse potential. Use of prescription sedative-hypnotics—for example, the nonbenzodiazepine Z-drugs—often leads to a relapse back into ...
Commonly prescribed benzodiazepines in the U.S. are Valium (diazepam) and Ativan (lorazepam), which are used for muscle relaxation and to control anxiety and seizures. While Rohypnol falls into ...
The movie, premiering this month, is based on real events in the early 1990s, when a group of young people in Cuba were looking for freedom from government repression.
Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1]
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