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Cause histamine release, so greater side effects comparing with Atracurium; Rarely used Atracurium: Safer alternative to tubocurarine with less side effects; Surgical anaesthetic & intubation facilitate endotracheal intubation and provide skeletal muscle relaxation to reduce the risk of laryngeal injury. [12]
Both dicyclomine and hyoscyamine are antispasmodic due to their anticholinergic action. [medical citation needed] Both of these drugs have side effects common to anticholinergics and can worsen gastroesophageal reflux disease (GERD). [2] Papaverine is an opium alkaloid used to treat visceral spasms, particularly those of the intestines. [3]
A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone. It may be used to alleviate symptoms such as muscle spasms , pain , and hyperreflexia . The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics .
Adverse effects occur in fewer than 1% of patients and include muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia, and dry mouth. All effects are reversible. [3] [4] Allergic reactions occur in fewer than 0.1% of patient and include skin rash, hives, Quincke's edema, and in some cases anaphylactic shock. [3] [7] [8] [9]
Metaxalone, sold under the brand name Skelaxin, is a muscle relaxant medication used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. [1] Its exact mechanism of action is not known, but it may be due to general central nervous system depression. [1]
Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures. [8] [9] Until the beginning of the 20th century, anticholinergic drugs were widely used to treat psychiatric disorders. [10]
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.
Side effects of thiocolchicoside can include nausea, allergy and vasovagal reactions. [15] Liver injury, pancreatitis, seizures, blood cell disorders, severe cutaneous disorders, rhabdomyolysis, and reproductive disorders have all been recorded in the French and European pharmacovigilance databases and in the periodic updates that the companies concerned submit to regulatory agencies.
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