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Paroxetine, sold under the brand name Paxil among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] It is used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Very common (10-100% incidence) adverse effects include: Nausea; Sexual dysfunction (including anorgasmia (difficulty achieving an orgasm), erectile dysfunction, genital anaesthesia, ejaculation disorder, loss of libido etc.).
When discontinuing an antidepressant with a short half-life, switching to a drug with a longer half-life (e.g., fluoxetine or citalopram) and then tapering, and eventually discontinuing, from that drug can decrease the severity of symptoms in some cases.
The term "third generation antidepressant" is sometimes used to refer to newer antidepressants, [1] from the 1990s and 2000s, often selective serotonin reuptake inhibitors (SSRIs) such as; fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft), as well as some non-SSRI antidepressants such as mirtazapine, nefazodone, venlafaxine ...
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Paxil – an antidepressant of the SSRI class; Nardil – an antidepressant of the MAOI class used to treat depression; Orap – a typical antipsychotic used to treat tic disorder; Pristiq (desvenlafaxine) – an antidepressant of the SNRI class; Prolixin (fluphenazine) – typical antipsychotic
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The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, generalized anxiety disorder, panic disorder, obsessive–compulsive disorder (OCD), eating disorders, chronic pain, and, in some cases, for posttraumatic stress disorder (PTSD).