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Diarrhea is a well-known side effect of metformin. Learn more about why this gut-related side effect happens and how to manage it. Does Metformin Cause Diarrhea?
The most common side effects are gastrointestinal (everyone’s favs: diarrhea, bloating, stomach pain, gas, indigestion and constipation). These affect up to 30 percent of metformin users.
The most common side effects of metformin include: Diarrhea. Nausea. Vomiting. Upset stomach. Weakness. ... Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset ...
Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.
Caffeine lowers the resting tone of the anal canal and also causes diarrhea. Excessive doses of vitamin C, magnesium, phosphorus and/or calcium supplements may increase FI. Reducing the olestra fat substitute, which can cause diarrhea, may also help. [37]
Other causes of stomach rumbles: Incomplete digestion of food can lead to excess gas in the intestine. In humans, this can be due to incomplete digestion of carbohydrate-containing foods, including milk and other dairy products (lactose intolerance or the use of α-glucosidase inhibitors by diabetics), gluten (protein in wheat, barley, and rye) (coeliac disease), fruit, vegetables, beans ...
Diarrhea. Flatulence. Asthenia (feeling weak or lacking energy) Stomach pain. Headache. Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication ...
Apparently, the (unknown) mechanism of induction of diarrhea caused by metformin is different than for ordinary diarrhea. A distinguishing feature of metformin-induced diarrhea is that it is associated with strong, painful intestinal cramping that occurs irrespective of what is in the colon. The initial bowel motions may be quite solid.
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