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  2. Clopidogrel - Wikipedia

    en.wikipedia.org/wiki/Clopidogrel

    A box of Plavix. Plavix is marketed worldwide in nearly 110 countries, with sales of US$6.6 billion in 2009. [45] It was the second-top-selling drug in the world in 2007 [46] and was still growing by over 20% in 2007. US sales were US$3.8 billion in 2008. [47] Before the expiry of its patent, clopidogrel was the second best-selling drug in the ...

  3. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Oral Antiplatelet Drugs UK Trade Name Other Names (Non-UK) Aspirin: Nu-Seals, Microprin, caprin Dual with dipyridamole: Asasantin Retard, Molita Modified Release acetylsalicylic acid - There are numerous brand names for Aspirin Clopidogrel: Plavix, Grepid Iscover Dipyridamole: Persantin, Persantin Retard, Attia Modified Release, Ofcram PR.

  4. P2Y12 - Wikipedia

    en.wikipedia.org/wiki/P2Y12

    A network meta-analysis of 37 studies involving 88,402 STEMI patients and 5,077 major adverse cardiac events (MACE) patients found that use of prasugrel was associated with lower mortality and MACE than other drugs in this class (clopidogrel and ticagrelor). [16]

  5. Adenosine diphosphate receptor inhibitor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_diphosphate...

    Like other thienopyridine drugs, the drug was often combined with aspirin in clinical use. [23] The clinically approved dosage of clopidogrel is a 300-mg loading dose PO and a 75-mg a day maintenance dose PO. [28]

  6. The 10 Biggest-Selling Drugs That Are About to Lose Their Patent

    www.aol.com/news/2011-02-27-top-selling-drugs...

    Plavix. This anti-clot or blood thinner most prescribed to prevent heart attack or stroke claims the title of second-best selling drug in the world, with $9.4 billion in global sales in 2010.

  7. Prasugrel - Wikipedia

    en.wikipedia.org/wiki/Prasugrel

    Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...

  8. Blood thinners, diabetes meds among first 10 drugs for US ...

    www.aol.com/news/us-names-first-10-drugs...

    Medicare, which mostly serves Americans aged 65 and over, pays twice as much for drugs than the U.S. Department of Veterans Affairs, which already negotiates drug prices, he said.

  9. Thienopyridine - Wikipedia

    en.wikipedia.org/wiki/Thienopyridine

    Ticagrelor (Brilinta) is often listed with thienopyridine inhibitors and has similar indications for use but is not a thienopyridine. It is a cyclo-pentyltriazolo-pyrimidine that is distinct from the mechanism of the thienopyridines in that it reversibly (rather than irreversibly) inhibits the P2Y 12 receptor.

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