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  2. Temgicoluril - Wikipedia

    en.wikipedia.org/wiki/Temgicoluril

    Temgicoluril (INN Tooltip International Nonproprietary Name), [2] also known as tetramethylglycoluril and sold under the brand names Adaptol and Mebicar, is an anxiolytic medication produced by Latvian pharmaceutical company Olainfarm and sold in Latvia and Russia.

  3. Picamilon - Wikipedia

    en.wikipedia.org/wiki/Picamilon

    Picamilon (also known as N-nicotinoyl-GABA, pycamilon, and pikamilon) is a drug formed by a synthetic combination of niacin and γ-aminobutyric acid (GABA). It was developed in the Soviet Union in 1969 [3] and further studied in both Russia [4] and Japan as a prodrug of GABA. [5] In Russia, picamilon is sold as a prescription drug.

  4. Vigabatrin - Wikipedia

    en.wikipedia.org/wiki/Vigabatrin

    Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...

  5. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    Gabapentin at a low dose of 100 mg has a T max (time to peak levels) of approximately 1.7 hours, while the T max increases to 3 to 4 hours at higher doses. [1] The T max of pregabalin is generally less than or equal to 1 hour at doses of 300 mg or less. [ 1 ]

  6. Homotaurine - Wikipedia

    en.wikipedia.org/wiki/Homotaurine

    Homotaurine has been reported as a GABA antagonist, [4] as well as a GABA agonist. [10] [11] In vitro studies have found that homotaurine is a GABA A partial agonist [12] as well as a GABA B receptor partial agonist with low efficacy, becoming an antagonist and displacing the full agonists GABA and baclofen at this receptor. [13]

  7. Golden Retriever Relies on 'Emotional Support Bucket' to ...

    www.aol.com/golden-retriever-relies-emotional...

    Separation anxiety, where dogs suffer from being left alone, can cause them to engage in destructive behaviors like tearing up furniture or belongings or urinating and defecating in the house ...

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