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Diagnosis is not always straightforward as serum levels can be falsely high or normal. [10] Elevated methylmalonic acid levels may also indicate a deficiency. [2] Individuals with low or marginal values of vitamin B 12 in the range of 148–221 pmol/L (200–300 pg/mL) may not have classic neurological or hematological signs or symptoms. [2]
A diagnosis of vitamin B 12 deficiency is determined by blood levels lower than 200 or 250 picograms per ml (148 or 185 picomoles per liter). [3] Some people can have symptoms with their normal levels of the vitamin, or may have low levels despite having no symptoms. [5] Other tests may be done to ensure individuals status. [3]
Normal serum levels may be found in cases of deficiency where myeloproliferative disorders, liver disease, transcobalamin II, or small intestinal bacterial overgrowth are present. [ 56 ] [ 57 ] Low levels of serum vitamin B 12 may be caused by other factors than B 12 deficiency, such as folate deficiency , pregnancy , oral contraceptive use ...
A vitamin B12 level of less than 200 pg/mL is considered deficient. Treatment First, have your health care provider run blood tests to see if you truly have a B12 deficiency.
Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
A B12 deficiency can cause issue ranging from ... Everyone requires a certain amount of B12 depending on their age, starting with .5 mcg per day for infants up to 2.4 mcg for teens and adults and ...
The main type of vitamin B12 deficiency anemia is pernicious ... as it is seen in people with B 12 deficiency, ... even in some cases with normal blood B 12 levels.
But having lower vitamin B12 levels doesn’t automatically mean that someone’s symptoms are being caused by the deficiency. “B12 deficiency is also more common in people with Alzheimer’s ...