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Ertugliflozin, sold under the brand name Steglatro, is a medication used for the treatment of type 2 diabetes. [ 3 ] [ 4 ] The most common side effects include fungal infections of the vagina and other infections of the female reproductive system.
Ertugliflozin was approved in the United States under the brand name Steglatro in December 2017. [32] Ipragliflozin, produced by the Japanese company Astellas Pharma Inc. under the brand name Suglat, approved in Japan January 2014. [33] [34]
This listing is limited to those independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the pharmaceutical industry at some time in their existence, provided they were engaged in the production of human (as opposed to veterinary) therapeutics.
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Thiazolidinedione ligand dependent transactivation is responsible for the majority of anti-diabetic effects. The activated PPAR/RXR heterodimer binds to peroxisome proliferator hormone response elements upstream of target genes in complex with a number of coactivators such as nuclear receptor coactivator 1 and CREB binding protein, this causes upregulation of genes (for a full list see PPARγ):
This list comprises the largest companies currently in the United States by revenue as of 2024, according to the Fortune 500 tally of companies and Forbes.. The Fortune 500 list of companies includes only publicly traded companies, also including tax inversion companies.
A study funded by Novo Nordisk, the U.S. distributor for Repaglinide, compared their product with Nateglinide in "A randomized, parallel-group, open-label, multicenter 16-week clinical trial". [1]
ADTRAN/BlueSocket; Aerohive Networks - acquired by Extreme Networks [1]; Alaxala Networks; Alcatel-Lucent Enterprise; Allied Telesis; Alvarion; Aruba - acquired by HPE; Asus; Avaya; AVM; Belkin
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"The lowest prices on specific drugs" - Family Circle